College Football Picks and Predictions Against the Spread for Top 25 Games in Week 13
Week 13 of the 2022 college football season features several high-profile and intriguing matchups to bet against the spread, including Notre Dame-USC, Michigan-Ohio State, Oregon-Oregon State, and Florida-Florida State. Also, the Week 13 slate includes Baylor-Texas, Iowa State-TCU, LSU-Texas A&M, Michigan State-Penn State, South Carolina-Clemson, and Auburn-Alabama. And if you are looking to wager or bet against the spread on any of these games or Top 25 contests, our NCAA experts are ready with their predictions and picks.
Related: College Football Predictions for Every Game in Week 13
Athlon Sports picks the 21 matchups involving the top 25 teams, according to the latest College Football Playoff rankings, against the spread for Week 13:
| Spread | Steven Lassan | Mark Ross | Ben Weinrib | |
|---|---|---|---|---|
Mississippi State at No. 20 Ole Miss (Thanksgiving) | MISS -2 | Ole Miss | Ole Miss | Ole Miss |
No. 19 Tulane at No. 24 Cincinnati (Fri.) | CIN -2 | Cincinnati | Cincinnati | Cincinnati |
Baylor at No. 23 Texas (Fri.) | TEX -8.5 | Texas | Texas | Texas |
NC State at No. 17 North Carolina (Fri.) | UNC -6.5 | NC State | NC State | NC State |
No. 18 UCLA at California (Fri.) | UCLA -10 | UCLA | UCLA | UCLA |
Florida at No. 16 Florida State (Fri.) | FSU -9.5 | Florida | Florida State | Florida |
No. 25 Louisville at Kentucky | UK -3 | Kentucky | Louisville | Kentucky |
No. 22 UCF at USF | UCF -19.5 | UCF | UCF | UCF |
No. 14 Utah at Colorado | UTAH -29.5 | Utah | Utah | Utah |
No. 13 Washington at Washington State | WASH -2 | Washington | Washington | Washington State |
Kansas at No. 12 Kansas State | KSU -12 | Kansas State | Kansas | Kansas State |
Michigan State at No. 11 Penn State | PSU -18 | Penn State | Penn State | Penn State |
No. 10 Tennessee at Vanderbilt | TENN -14 | Vanderbilt | Vanderbilt | Vanderbilt |
No. 9 Oregon at No. 21 Oregon State | ORE -3 | Oregon | Oregon | Oregon |
South Carolina at No. 8 Clemson | CLEM -14.5 | Clemson | Clemson | South Carolina |
Auburn at No. 7 Alabama | ALA -22 | Auburn | Auburn | Alabama |
No. 15 Notre Dame at No. 6 USC | USC -5.5 | Notre Dame | USC | USC |
No. 5 LSU at Texas A&M | LSU -10 | LSU | LSU | LSU |
Iowa State at No. 4 TCU | TCU -10 | TCU | TCU | TCU |
No. 3 Michigan at No. 2 Ohio State | OSU -7.5 | Ohio State | Michigan | Michigan |
Georgia Tech at No. 1 Georgia | UGA -35.5 | Georgia | Georgia Tech | Georgia |
Podcast: Week 13 Preview, Predictions & Picks Against the Spread. Breakdown of the Latest CFB Playoff Rankings and Coaching News and Rumors
